Whereas CD97 and CD142 (Tissue Factor), for which a pro-invasive phenotype of GBM cells was already shown [37,38], were not regulated by either ACT-209905 or THP-1 cells, the surface expressions of CD54 (ICAM1), CD62P (P-Selectin) and CD166 (ALCAM) were significantly regulated by ACT-209905, thus arguing for their role in the migration of GBM cells. The gene discussed is ALCAM; the disease is glioblastoma.