PDX1 and neoplasm: Listeria-TT856–1313 used in combination with low dose gemcitabine in advanced PDAC KrasG12D,p53R172H,Pdx1-Cre (KPC) murine models reduced tumour growth, tumour metabolic activity and tumour burden by 80%, metastasis by 87% and increased survival by 40% compared to non-treated mice.