Angiogenesis, which promotes cancer metastasis and the progression of the disease, has been found to be positively correlated with the dysregulation of the Ki-ras2 Kristen rat sarcoma viral oncogene homolog/YY1/zinc finger protein 322/sonic hedgehog signaling molecule (Kras/YY1/ZNF322/Shh) transcriptional axis [32]. Here, ZNF322 is linked to cancer.