Adiponectin silencing in 22RV1 cells—human prostate cancer cell—downregulates the expression of epithelial markers: E-cadherin and zonula occludens-1 (ZO-1), but upregulates the expression of mesenchymal markers: zinc finger E-box binding homeobox 1 (ZEB1), vimentin and Snail. This evidence concerns the gene ZEB1 and prostate cancer.