The most common mutations noted in HCC include TERT, TP53, CTNNB1, AXIN1, ARID1A, CDKN2A, and CCND1 genes (Table 2) [24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44]. This evidence concerns the gene TERT and hepatocellular carcinoma.