CD8A and neoplasm: Melanoma-bearing mice exposed to [109] fenofibrate and a recombinant chimpanzee-derived replication-defective adenoviral vector expressing T-cell epitopes of melanoma-associated antigens (AdC68-gDMelapoly) exhibited ameliorated metabolic stress symptoms and delayed tumor progression by vaccine-induced circulating and tumor-infiltrating CD8+ T-cells.