All 12 RBPs involved in NSCLC (IGF2BP1/2/3, HuR, FBL, EIF4A3, WDR5, YTHDF1, hnRNPD, hnRNPK, and hnRNPU) contributed to the stability of target mRNAs. The gene discussed is YTHDF1; the disease is non-small cell lung carcinoma.