EGFR and non-small cell lung carcinoma: In the LUX-Lung 7 study, afatinib exhibited significantly longer PFS (median 11.0 months with afatinib vs. 10.9 months with gefitinib) and time-to-treatment failure (median 13.7 months with afatinib vs. 11.5 months with gefitinib) compared with gefitinib as a first-line treatment for EGFR mutation-positive NSCLC patients [16].