TNF and autoimmune disease: The components of the panel include potent inflammatory factors such as TNF-α, IL-1Ra, IL-1β, IL-6, IFN-γ, and GM-CSF involved in the pathogenesis of various inflammatory and autoimmune diseases, cytokines with activating/homeostatic functions produced by lymphocytes such as IL-2, anti-inflammatory factors, and factors involved in type 2 alternative inflammation such as IL-4 and IL-10.