IL5 and systemic lupus erythematosus: As for IL-5 and IL-13, the typical Type 2 cytokines which are also widely recognized as anti-inflammatory, studies have shown that IL-5/IL-13-secreting cell subsets were not significantly different between SLE patients and controls [33], which may help explain the unchanged IL-5/IL-13 levels between the SLE patients and healthy controls that we observed.