In addition, it has been shown that ILC2, which is characterized by the release of type 2 cytokines including IL-5, IL-9, and IL-13, etc., regulates a number of immune responses and functions protectively in autoimmunity by inhibiting the synthesis of IL-27 and by generating IL-9 to interact with regulatory T cells [18,29]. This evidence concerns the gene IL9 and Autoimmunity.