Changes in the antioxidant system of granulocytes taken form the peripheral blood of COVID-19 patients indicates an increased response to SARS-CoV-2 infection at the level of transcription factor Nrf2 and its phosphorylated form, as well as of the basic product of its transcriptional activity, i.e., heme oxygenase (HO-1), when compared to the values obtained for the control group (Figure 1). The gene discussed is HMOX1; the disease is COVID-19.