DIO3OS and inflammatory bowel disease: In terms of the observed differences in the expression levels of lncRNAs that have also been found in IBD (e.g., DPP10-AS1, KIF9-AS1, LINC01272, and DIO3OS), among the most important features that are encompassed in their potential as biomarkers, there are their gene regulatory mechanisms as well as their epigenetic modulation potential, which enables their variable expression in multiple disease states.