MSCs are able to deliver a variety of cytokines and growth factors to the tumor site that were identified as anti-tumor agents, comprising IFN-α, IFN-β, IFN-γ, IL-2, IL-7, IL-12, IL-15, IL-18, IL-25, and NK4, an antagonist of HGF [208,275,276]. This evidence concerns the gene HGF and neoplasm.