In the current study, we found that the expression levels of SLCs in mitochondria, including Slc25a3, Slc25a4, Slc25a5 and Slc25a30, were significantly up-regulated in the DDCs of CD-PC (Figure S6C) and might lead to an increase in ROS and enable the latter to act as a signaling molecule to activate tubular cell apoptosis in DKD [22]. This evidence concerns the gene SLC25A30 and diabetic kidney disease.