SUMO2 and p62/sequestosome-1 (p62/SQSTM1) proteins have been observed to accumulate in intranuclear inclusions isolated from postmortem FXTAS brain tissue [11], while tenascin-C (TNC), cluster of differentiation 38 (CD38), and phosphoserine aminotransferase 1 (PSAT1) have been observed in FXTAS cortex [12]. Here, SUMO2 is linked to fragile X-associated tremor/ataxia syndrome.