This results in incomplete destruction of bacteria (a process in which the Treg CD4+CD25+ lymphocytes may participate partially) and their multiplication and dissemination in the entire body; due to the significant antigenic strength of the surviving pathogens, this may lead, in the further course of the disease, to massive cytokine activation, which ends in the development of SIRS and septic shock and the patient’s death. The gene discussed is CD4; the disease is systemic inflammatory response syndrome.