The expression of several race-associated genes was also dependent on the MED12 mutation status of the tumor, being higher (FRAT2, TNFRSF19, ACP7, IRS4, PLEKHG4B, KRT17, SLN, and ZNF703) or lower (CAV2) in the mutated specimens compared with wild-type tumors. The gene discussed is IRS4; the disease is neoplasm.