Bawa et al. showed that a comprehensive assessment of neutrophil-associated inflammatory biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL), myeloperoxidase (MPO), Interleukin-8 (IL-8), macrophage inflammatory protein 1β (MIP-1β), and tumor necrosis factor (TNF) can predict deterioration in functioning in patients with dementia over the course of a year [36]. This evidence concerns the gene CXCL8 and dementia.