Importantly, a protective role of the TaqI (TT) genotype was repeatedly shown to be present both in Asian and Caucasian MS patients [28,29], and a study in Italian MS patients showed a protective role against MS risk for VDR TaqI (TT) subjects expressing HLA-DRB1*15.01 [11]. The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.