Indeed, pro-inflammatory bacteria and their components([i.e., lipopolysaccharides (LPS)), along with a damaged intestinal epithelial barrier, contribute to the establishment of a chronic low grade inflammatory status characterized by the expression of TNF-α, IL-6, IL-1β, and vascular endothelial growth factor (VEGF), which favour AMD onset [61]. The gene discussed is VEGFA; the disease is age-related macular degeneration.