BMP2 and intervertebral disk degenerative disorder: When LMP-1 was introduced into the rabbit IVD tissue in vivo, an increase in the expression of anti-inflammatory cytokines, bone morphogenetic proteins 2 and 7 (BMP-2, BMP-7), and aggrecan was observed, which confirms the expediency of using this factor as a new high-tech method for IDD in humans [46].