infections (TRIM5, 13, 14, 15, 18, 19, 20, 21, 22, 25, 26, 31, 35, 36, 37, 50, 55, 56, 61, 63, 65, 69, and 71) were up-regulated following TLR stimulation and/or by IFNs (Table S2), while TRIM59 and TRIM66 were down-regulated under these conditions and upon P. aeruginosa infection (Table S2). The gene discussed is TRIM5; the disease is infection.