infections with known data concerning the regulation of TRIM genes under stimulation of TLRs [15] or treatment by IFNs [16] revealed similar activation of many TRIM genes (TRIM5, 6, 10, 13, 14, 15, 18, 19, 20, 21, 22, 25, 26, 31, 34, 35, 36, 37, 50, 55, 61, 63, 65, 69, 71 (in A549), 56, 58 (in mouse lungs)) (Table S2 and S3). The gene discussed is TRIM5; the disease is infection.