It is important to highlight that the basic autophagic proteins, Beclin-1, LC3, and p62, were analyzed in the same context of the EAE/MS murine model but in different regions of the CNS, as the hippocampus in our study and the spinal cord in the research by Feng and co-authors, 2017, contribute differently to the activation and, consequently, to the role of autophagy in damaged neurons. Here, MAP1LC3A is linked to myeloid sarcoma.