Therefore, we propose that instead of influencing CD36 expression, decreased STIM1 expression in diabetic cardiomyopathy could increase FA uptake by the relocation of CD36 to the sarcolemma through the inactivation of the AKT–mTORC1–v-ATPase signaling pathway (Figure 5➀). This evidence concerns the gene AKT1 and diabetic cardiomyopathy.