We did not find changes between groups in either SOCS1 (1.36 ± 0.21 e-RA vs. 1.19 ± 0.2e-RA+TOFA vs. 17 ± 0.19 healthy, p = ns) or SOCS3 (1.02 ± 0.2 e-RA vs. 0.82 ± 0.19 e-RA+TOFA vs. 1 ± 0.15 healthy, p = ns) (Figure 6B). This evidence concerns the gene SOCS1 and rheumatoid arthritis.