HDAC6 and infection: In the regulation of MT dynamics during HIV-1 early infection, the acetylation-deacetylation balance is known to be decisive and carried out by histone deacetylase 6 (HDAC6) [71,74,75,163,164,165,166,167,168], an enzyme mainly located in the cytoplasm that regulates the deacetylation of the α-tubulin subunit in MTs [168,169,170,171,172].