VEGFA and hepatocellular carcinoma: The KEGG and REACTOME enrichment analysis revealed an association with focal adhesion, extracellular matrix (ECM) receptor interaction, axon guidance, vesicle-mediated transport, and VEGF signaling (Table 1), indicating the important role of HBV-HCC-released exosomes in the promotion of invasion and metastasis cascade including angiogenesis, EMT, invasion, migration, and establishment of a premetastatic niche.