For instance, THC could disrupt mitochondrial function, inhibit respiration and could result in cell death [109,110], and it could biphasically affect complex 1 function [111], while it could also restore mitochondrial function, possibly via activation of the peroxisomal proliferating activate receptor gamma (PPARγ), in a neuroblastoma cell line [112]. This evidence concerns the gene PPARG and neuroblastoma.