ANXA2 and cancer: The enhancer linked to ANXA2 is significantly enriched in the cancer-epithelial cells but not in the non-malignant cell types (log2FC = 2.3 and FDR < 0.001), resulting in significantly higher expression of ANXA2 as measured by the scRNA-seq (Wilcoxon rank sum tests, p-value < 2.22 × 10−16) (Figure 4C).