Interestingly, the other upregulated genes are associated with features of cell proliferation (TNFRSF12A in human hepatocellular carcinoma [61]), tumor progression (ISG20 in clear cell renal cell carcinoma [62]), and cell survival (LGALS3 in breast cancer [63]). The gene discussed is TNFRSF12A; the disease is hepatocellular carcinoma.