POU2F1 and cancer: Additionally, the gene targets of these miRNAs included several cancer driver genes including ZNF704 (targeted by ten miRNAs), MMP16 (targeted by eight miRNAs), and KCNN3, POU2F1, ADARB1, MPZL1, RUNX1T1, UBE2W, and DYRK1A genes (targeted by seven miRNAs).