It seems that the clinical expression of the homozygous MCPggaac haplotype depends significantly on additional mutations in the aHUS spectrum, especially CFH and CFI, and if so, various infectious diseases or even drugs trigger aHUS in children who are genetically prone to aHUS onset [1,2,8,9,29,33,34,35,36,37]. The gene discussed is CFH; the disease is infectious disease.