Similarly, in patients with HF, including HF of hypertensive origin, decreasing left atrial emptying function (LAEF), as measured by cardiac magnetic resonance (CMR) imaging, was associated with impairment of different cardiac function measurements like left ventricular ejection fraction (LVEF) or right ventricular ejection fraction (RVEF), higher circulating biomarkers like circulating N-terminal pro-brain natriuretic peptide (NT-proBNP), and worse prognosis in terms of survival [27,28]. This evidence concerns the gene NPPB and hydrops fetalis.