In non-small cell lung carcinoma, URG4 expression is correlated with the expression of MMP-9 expression, which is positively correlated in various cohorts of human NSCLC specimens, and NF-κB-activated MMP-9 expression contributes to the URG4-induced invasiveness of NSCLC cell lines [15]. The gene discussed is NFKB1; the disease is non-small cell lung carcinoma.