Combinations of these factors have resulted in the development of predictive indices or models, such as pre-Moral (including NLR, maximum AFP level, or largest tumor size), post-Moral (involving size and the number of nodules, vascular invasion and degree of differentiation in the explant), Combo-Moral (a composite score derived from both the pre-Moral and post-Moral scores) and the RETREAT model (a composite score calculated based on AFP level at LT, presence of microvascular invasion, and some of the largest viable tumor diameter plus the number of viable nodules) [12,13]. Here, AFP is linked to neoplasm.