Markers that were significantly elevated in the MIS-C training cohort compared to the COVID-19 training cohort are CRP (median 15.9 mg/dL, p = 5.2×10−10), ferritin (median 333.3 mg/L, p = 7.2×10−3), procalcitonin (median 4.7 ng/mL, p = 4.6×10−9), fibrinogen (median 513 mg/dL, p = 1.8×10−5), protime (median 15.4 s, p = 1.6×10−4), D-dimer (median 3.0 μg/mL, p = 1.4×10−7), BNP (median 221.6 pg/mL, p = 1.5×10−7) and the neutrophil to lymphocyte ratio (NLR), (median 8.0, p = 3.3×10−4). Here, NPPB is linked to COVID-19.