In the plasma, the miRNA-181b-5p was upregulated 24 h after surgery and downregulated in GH-secreting patients compared to non-functioning pituitary NET patients, whereas miRNA-181a-2-3p was upregulated in GH patients 24 h after surgery and downregulated in GH patients before surgery compared to non-functioning patients before surgery [145]. The gene discussed is GH1; the disease is hypophysitis.