The authors found a significant decrease in the mean ECP serum values under topical fluticasone treatment, and a concordant shift in serum ECP and eosinophilic count in 87% of patients, also paralleling a subjective improvement in symptoms, suggesting a possible role for serum ECP in the monitoring of EoE [36]. Here, RNASE3 is linked to eosinophilic esophagitis.