SREBF1 and non-alcoholic fatty liver: In a study conducted by Liu et al., the prevention of NAFL due to oat β-glucan supplementation was contributed by the activation of the AMPK signaling pathway, which was accompanied by downregulation of hepatic lipogenic protein expression including phosphorylated acetyl-CoA carboxylase, fatty acid synthase and sterol regulatory element-binding protein 1 (SREBP1) [49].