Foreign pathogen invasion is recognized by cellular receptors after a series of signal transduction events, activating the IκB kinase complex (IKK), in turn inducing release of NF-κB dimers, and finally activating the NF-κB pathway [40], which induces inflammatory responses and tumor formation and promotes the release of inflammatory factors and tumor necrosis factors [41,42]. The gene discussed is NFKB1; the disease is neoplasm.