PAPSS1 and neoplasm: To further investigate the effect of PAPSS1 on tumor growth, nude mice were inoculated subcutaneously with A2780 and SKOV3 cells transfected with sh-PAPSS1 or shSCR, followed by cisplatin treatment (0.3 or 3 mg/kg) used for both ovarian tumor xenografts derived from A2780 and SKOV3 cells.