Moreover, the proportion of CD19+IL-10+Breg cells in lymphocytes of control pregnant mice, GDM mice, and GDM mice treated with probiotics was (0.59 ± 0.04)%, (0.13 ± 0.03)% (p = 0.0006, comparison between control pregnant mice and GDM mice), and (0.52 ± 0.12)% (p = 0.0016, comparison between GDM mice and GDM mice treated with probiotics), respectively (Fig. 6B). The gene discussed is IL10; the disease is gestational diabetes.