Carvalho reported that exosomes from ABC-DLBCL cell lines contained more CCDC50 proteins than GCB cell lines, indicating that DLBCL-derived exosomes carry CCDC50 proteins and exosomal CCDC50 showed significantly different levels in DLBCL subtypes [18]. The gene discussed is CCDC50; the disease is diffuse large B-cell lymphoma.