For myeloid malignancies, individuals with only CHIP mutations (HR = 5.44, 95% CI = 3.97–7.47, P = 9.00 × 10−26) or only autosomal mCAs (HR = 7.19, 95% CI = 5.32–9.70, P = 6.14 × 10−38) were associated with increased risk. The gene discussed is STUB1; the disease is myeloid neoplasm.