Here, we perform a systematic investigation examining genetic and phenotypic associations across all types of CH utilizing a spectrum of genotyping and sequencing data from large-scale genetic susceptibility studies of types of clonal hematopoiesis (e.g., mCAs, LOX, LOY, and CHIP), hematologic malignancies (e.g., myeloproliferative neoplasms (MPNs)), and hematopoietic phenotypes. The gene discussed is LOX; the disease is myeloproliferative neoplasm.