We found that 12 LOY loci, mapping to 11 genes (TET2, NREP, GFI1B, TERT, DLK1, PARP1, TP53, RBPMS, MAD1L1, MECOM, and ATM) co-localized with MPN (Supplementary Data 24), highlighting 6 loci that have not previously reached genome-wide significance for MPN (P = 1.17 × 10−4 to 5.14 × 10−8). Here, MECOM is linked to myeloproliferative disorder.