To distinguish the infected cells at the single-cell level, MX1-positive cells were considered ZIKV-infected trophoblast cells since MX1 is known to be increased after ZIKV infection, which was also demonstrated in ZIKV-infected hTSCs, STBTS and EVTTS (Fig. 3f and g). The gene discussed is MX1; the disease is Zika virus infectious disease.