With KEGG enrichment analysis, the key enriched pathways for DEGs were “PI3K-Akt signaling pathway”, “Regulation of actin cytoskeleton”, “cAMP signaling pathway”, “Coronavirus disease – COVID-19”, “Tight junction”, “Transcriptional misregulation in cancer”, “Thyroid hormone signaling pathway”, “Alcoholic liver disease”, “Platelet activation”, and “Autophagy - animal” (Supplementary Figure 1C, 1D). This evidence concerns the gene AKT1 and alcoholic liver diseases.