In addition, compared to non-adjacent normal tissues using TCGA datasets, a significant up-regulation of AKAP8L expression was observed in 14 cancer types, such as BRCA, CHOL, COAD, ESCA, HNSC, KICH, KIRC, kidney renal papillary cell carcinoma (KIRP), LIHC, Lung adenocarcinoma (LUAD), LUSC, Prostate adenocarcinoma (PRAD), READ, as well as STAD (Figure 1D). This evidence concerns the gene AKAP8L and lung adenocarcinoma.