CD8A and head and neck squamous cell carcinoma: Immune cells including, neutrophils, B cells, and CD8+ T cells, were shown to be more plentiful in the tissue and blood of HNSCC subjects with a positive prognosis.[55] CIBERSORT studies found low infiltration levels of CD8+ T cells and naive B cells in high-risk individuals, which may be a factor in their worse prognosis.