Removal of ELOVL6 will increase insulin sensitivity and reduce insulin resistance, so that some patients with type 2 diabetes can be cured.[10] More studies have shown that ELOVL6 plays an important role in the occurrence and development of breast cancer,[11] colon cancer,[12] liver cancer,[13] and lung squamous cell carcinoma.[14] However, there are still few reports about ELOVL6 in LUAD. Here, ELOVL6 is linked to malignant colon neoplasm.