KEGG analysis showed that 169 signaling pathways (P < .05) were involved in Pathways in cancer, Lipid and AS, Chemical carcinogenesis - receptor activation, advanced glycosylation end product-receptor of AGE (AGE-RAGE) signaling pathway in diabetic complications, and Hepatitis B, etc. In the study, the top 10 signal pathways were selected according to the P value to map a path bubble diagram, as shown in Figure 8. This evidence concerns the gene AGER and cancer.