Alterations in cell cycle genes due to the upregulation of their transcription factor, such as c-Myc, Forkhead Box F (FoxF1/FoxF2), and T-box transcription factor 3 (TBX3), are frequently found in leiomyosarcoma, osteosarcoma, chondrosarcoma, synovial sarcoma, and Ewing’s sarcoma (EwS) [23,24]. This evidence concerns the gene TBX3 and Ewing sarcoma.